http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109589340-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_157f6ea8a2b996328769d9b5e934655f
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-64
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-64
filingDate 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_230b0194818d5121175dc24b86419393
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45922bba0bcba4bdd1c22b776561f03d
publicationDate 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109589340-A
titleOfInvention Application of Mole Cricket Extract in the Preparation of Drugs for Treating Triple-Negative Breast Cancer
abstract The invention discloses the application of a mole cricket extract in preparing a medicine for treating triple-negative breast cancer. In this application, the preparation method of the mole cricket extract includes the following steps: (1) extracting the raw material mole cricket with petroleum ether and concentrating the extract under reduced pressure until the weight is basically unchanged; (2) adopting high-speed countercurrent chromatographic separation, wherein: The solvent system is a mixture of chloroform, methanol and water, the upper phase is a stationary phase, and the lower phase is a mobile phase; after collecting the eluent for 60-120 min, it can be concentrated under reduced pressure. The mole cricket extract has obvious inhibitory activity on triple-negative breast cancer cells in vitro.
priorityDate 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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