http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109574920-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-85 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 |
| filingDate | 2018-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109574920-B |
| titleOfInvention | 3-nitrile-6-cyclopropyl pyridine IDO1 inhibitor and application thereof |
| abstract | The invention relates to 3-nitrile-6 cyclopropyl pyridine IDO1 inhibitor and application thereof, wherein the inhibitor is a compound shown in a general formula I or pharmaceutically acceptable salt thereof, and n represents 1-4; r represents hydrogen, halogen, methyl, C 1 ~C 4 Alkoxy, cyano, nitro, C 1 ~C 4 An alkyl group. The 3-nitrile-6-cyclopropyl pyridine IDO1 inhibitor has the advantages of novel structure, high activity, small side effect and good drug metabolism property, and can be used as an anti-tumor candidate compound. The compounds can be used singly or in combination with other antitumor drugs, thereby achieving the effects of improving the curative effect of the existing antitumor drugs and reducing the dosage and toxicity. |
| priorityDate | 2018-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 332.