http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109574894-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C327-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-08 |
| filingDate | 2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109574894-B |
| titleOfInvention | Synthesis method of N- (3- (dimethylamino) -3-propylsulfonyl) -substituted benzamide (I) |
| abstract | The invention discloses a method for synthesizing N- (3- (dimethylamino) -3-propylsulfonyl) -substituted benzamide (I), which is prepared from substituted benzoylAllylamine (II), sulfur and N, N-Dimethylformamide (DMF) are directly prepared by sulfuration and amination of olefinic bond terminal carbon connected with saturated carbon atoms in the presence of a catalyst or without the catalyst, and the reaction formula is as follows: (ii) a Substituted benzoylallylamines (II) wherein R 1 ~R 5 The same or different hydrogen, alkyl, halogenated alkyl, aryl, halogen, nitro, sulfocarboxyl, carboxyl, ester group and cyano. The invention uses substituted benzoylallylamine (II) which is easily obtained in the market as an initial raw material, and quickly and conveniently obtains the N- (3- (dimethylamino) -3-propylsulfonyl) -substituted benzamide (I) through one-step reaction. The invention has the advantages of novel and convenient reaction process, mild and easily-controlled reaction conditions, simple reaction solvent system and easy post-treatment. |
| priorityDate | 2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.