http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109568608-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1863 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 |
| filingDate | 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109568608-B |
| titleOfInvention | A kind of polysaccharide-based nanoparticle contrast agent and preparation method thereof |
| abstract | The invention discloses a polysaccharide-based nanoparticle contrast agent and a preparation method thereof. The preparation method includes the following steps: Step 1: Dissolving glucan in water to prepare an aqueous solution of glucan with a concentration of 10-50 mg/mL Step 2, dissolving the initiator ceric ammonium nitrate in nitric acid to prepare an aqueous initiator solution; Step 3, dissolving the water-soluble crosslinking agent N,N-methylenebisacrylamide in water to prepare an aqueous solution of the crosslinking agent; Step 4, Under the protection of inert gas, the aqueous initiator solution is added to the aqueous dextran solution to induce free radicals. It can effectively prevent the contrast agent from entering the blood vessel, reduce the background noise of the MR tracer, and improve the specificity and time limit of the lymphatic pathway tracing. |
| priorityDate | 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.