http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109568605-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-045 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2018-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109568605-B |
| titleOfInvention | Magnetic composite diagnosis and treatment agent capable of realizing MRI (magnetic resonance imaging) monitoring and radio frequency ablation synergistic effect and preparation method and application thereof |
| abstract | The invention discloses a magnetic composite diagnosis and treatment agent capable of realizing MRI monitoring and radio frequency ablation synergistic effect, a preparation method and application thereof, wherein the magnetic composite diagnosis and treatment agent is composed of supported solid menthol and porous hollow Fe3O4 nano particles and is prepared by a simple liquid-solid mutual transformation mediated infusion method. The magnetic composite diagnosis and treatment agent enhances radio frequency ablation in a radio frequency field through the following two ways, namely, menthol carried in the agent realizes solid-liquid-gas three-phase conversion to generate transient cavitation, and simultaneously blocks heat loss and enhances radio frequency ablation; secondly, the porous Fe3O4 nano particles generate magnetic-thermal transition to further enhance the radio frequency ablation. In addition, the magnetic composite diagnosis and treatment agent is carried out along with radio frequency, the exchange rate and coordination number of the porous hollow Fe3O4 and water molecules are remarkably increased, so that the T1 weighted MRI effect is enhanced, and the monitoring of the radio frequency ablation process is realized. The product of the invention has mild preparation conditions, is simple and feasible, has no pollution and high yield, is suitable for industrialized large-scale production and has huge clinical transformation potential. |
| priorityDate | 2018-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.