http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109553786-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2305-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 |
| filingDate | 2017-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109553786-B |
| titleOfInvention | Vanillin cross-linked chitosan oligosaccharide mono-guanidine hydrochloride and microwave synthesis method thereof |
| abstract | The invention discloses vanillin cross-linked chitosan oligosaccharide mono-guanidine hydrochloride and a microwave synthesis method thereof, wherein a chitosan oligosaccharide product is used as a raw material, sulfur trioxide urea obtained by oxidation under the dual action of hydrogen peroxide and concentrated sulfuric acid is used as a guanylating reagent, vanillyl alcohol is used as a cross-linking agent, liquid phase synthesis reaction is carried out under the microwave condition to obtain a chitosan oligosaccharide hydrochloride derivative which is cross-linked by vanillin and has a mono-guanidine group, the chitosan oligosaccharide hydrochloride derivative is washed by ethanol for multiple times to be neutral, and finally, a solid is placed into a vacuum drier to be dried at the temperature of 40-80 ℃ until the water content of the material is less than 0.5-10%. The method has the advantages of simplicity, convenience, easy implementation, less side reaction and the like, and simultaneously introduces a guanidyl and a cross-linked structure into the chitosan oligosaccharide with good biocompatibility, so that the biological activity, the stability and the solubility of the chitosan oligosaccharide are obviously improved, and the chitosan oligosaccharide has wider application prospects in the fields of medicine, chemical industry, agriculture, food and the like. |
| priorityDate | 2017-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.