http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109553539-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-63 |
| filingDate | 2017-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109553539-B |
| titleOfInvention | Preparation method of benzalkonium chloride |
| abstract | The invention discloses a preparation method of benzalkonium chloride. The preparation method comprises the following steps of (1) carrying out salt-forming reaction on fatty alkyl dimethyl tertiary amine and benzyl chloride in an organic solvent at 30-70 ℃ to obtain fatty alkyl dimethyl benzyl ammonium chloride; the fatty alkyl is dodecyl, tetradecyl or hexadecyl; the organic solvent is one or more of methanol, ethanol, n-propanol, isopropanol, acetone and acetonitrile; (2) and (2) crystallizing a mixture containing two or three of the fatty alkyl dimethyl benzyl ammonium chlorides prepared in the step (1) in an organic solvent. The preparation method has simple process and high yield which can reach more than 90 percent; the method has the advantages of low content of related substances, high purity of over 99 percent, low water content, good appearance and form of the product, simple post-treatment, and suitability for industrial production of pharmaceutical benzalkonium chloride. |
| priorityDate | 2017-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.