http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109553524-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C63-70 |
| filingDate | 2017-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109553524-B |
| titleOfInvention | Synthetic method of 2, 4-dichloro-5-fluorobenzoyl chloride |
| abstract | The invention relates to a synthetic method of 2, 4-dichloro-5-fluorobenzoyl chloride serving as a quinolone drug intermediate. The synthesis method comprises the following steps: 2, 4-dichloro fluorobenzene, carbon dioxide and carbon tetrachloride are used for preparing 2, 4-dichloro-5-fluorobenzoyl chloride under the action of a cationic resin catalyst. The invention solves the problems of overlong process route, fussy post-treatment, high equipment requirement, use of highly toxic chemicals, low yield, poor quality and the like which are not suitable for industrial production in the prior art. The beneficial effects are that: the raw materials are cheap and easy to obtain, the process route is short, the production safety is good, the catalyst is easy to separate, the waste acid emission is less, the post-treatment is simple, the yield is high, the quality is good, and the method is suitable for industrial continuous production. |
| priorityDate | 2017-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.