http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109550035-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-39 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-8998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-8888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-9068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-718 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-752 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-284 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-344 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-076 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-9068 |
| filingDate | 2018-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109550035-B |
| titleOfInvention | New application of traditional Chinese medicine composition in preparation of antidepressant |
| abstract | The invention relates to the technical field of traditional Chinese medicines, in particular to application of a traditional Chinese medicine composition in preparation of antidepressant medicines, wherein the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-15 parts of immature bitter orange, 4-8 parts of bighead atractylodes rhizome, 4-8 parts of rhizoma pinellinae praeparata, 5-15 parts of coptis chinensis, 3-7 parts of codonopsis pilosula, 2-6 parts of liquorice, 2-6 parts of poria cocos, 4-12 parts of mangnolia officinalis, 2-6 parts of malt and 2-6 parts of dried ginger. Experiments show that the traditional Chinese medicine composition can improve the cell survival rate of a PC12 nerve cell damage model caused by corticosterone, recover the mitochondrial membrane potential, inhibit the expression of apoptosis genes and/or promote the expression of apoptosis inhibiting genes; the composition has the advantages that the immobility time of tail suspension and forced swimming of the mouse are obviously reduced, the content of 5-hydroxytryptamine in serum is increased, the depression-like behavior of the mouse is obviously improved, and the results show that the composition has obvious curative effect on depression. |
| priorityDate | 2018-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 160.