| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7155 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 |
| filingDate |
2013-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8dfd4fd1f80b9a06d842af2667a6c03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e09464a433b89ea9bf5043193b34ce0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18a65c1eaf6420215fdbe7055d8bcfd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6f3ca937e60fa10b86d28df91ef5c0c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09d3eda9364e7e3f8a070d5df5c1da95 |
| publicationDate |
2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109536526-A |
| titleOfInvention |
Nuclease-mediated targeting using large targeting vectors |
| abstract |
The present application provides compositions and methods for making one or more targeted genetic modifications at a target locus of a genome by using homologous recombination by a single-stranded or Double strand breaks promote the homologous recombination. The present application also provides compositions and methods for increasing the efficiency of homologous recombination between LTVECs and target loci of the genome in prokaryotic or eukaryotic cells using engineered nucleases. |
| priorityDate |
2012-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |