http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109535162-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
filingDate | 2018-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109535162-B |
titleOfInvention | Preparation method of N-p-aminobenzoyl glutamyl folic acid |
abstract | The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of N-p-aminobenzoyl glutamyl folic acid, which comprises the following steps: folic acid and p-aminobenzoyl glutamic acid are used as raw materials, organic alkali is added into an organic solvent, under the action of a condensing agent, a condensation activating agent and a catalyst, a crude product of N-p-aminobenzoyl glutamyl folic acid is generated through condensation reaction, and the N-p-aminobenzoyl glutamyl folic acid is obtained through preparative chromatographic separation. The invention provides a preparation method of N-p-aminobenzoyl glutamyl folic acid, which is used for the quality control of folic acid and is beneficial to further research on the generation mechanism and the control method of the N-p-aminobenzoyl glutamyl folic acid. |
priorityDate | 2018-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.