| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e2639e5c7757ab2f6379eaea83b1e40 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-175
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-09 |
| filingDate |
2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_973c637aeabf449d2265c7c2304f6ce8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b12b55f1d34957594b5e0cf6a69a09f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_808bfbbfda7c25984450f0d919041ca9 |
| publicationDate |
2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109534957-A |
| titleOfInvention |
A kind of synthetic method of chiral compound S-(-) -2- methyl -3- phenyl-1-propanol |
| abstract |
The invention discloses a kind of synthetic methods of chiral compound S-(-) -2- methyl -3- phenyl-1-propanol.Using α-methylcinnamaldehyde as raw material, catalytic hydrogenation reaction synthesis (±) -2- methyl -3- phenyl-1-propanol is first passed through；Monoesters is formed by esterification with phthalic anhydride again；Pass through acid-base reaction forming salt with R- (+)-α-phenylethylamine again later；Then by crystallization and recrystallization, single chiral isomers therein is isolated and purified；Then by hydrolysis, S- (-) -2- methyl -3- phenyl-1-propanol and hydrolysising by-product are obtained；It is finally separating purifying and removes hydrolysising by-product, obtain S- (-) -2- methyl -3- phenyl-1-propanol. |
| priorityDate |
2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |