http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109529101-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0023
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-008
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L26-00
filingDate 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109529101-B
titleOfInvention Tough hydrogel wound dressing capable of being rapidly degraded and preparation method thereof
abstract The invention discloses a tough hydrogel wound dressing capable of being rapidly degraded and a preparation method thereof, which are used for solving the technical problem that the existing wound dressing cannot be degraded. The technical scheme is that the wound dressing consists of a flexible network and a rigid network. The flexible network comprises a polycarboxy polymer and metal ions, and the rigid network is a polyacrylamide network containing disulfide bonds. Due to the introduction of disulfide bond groups, the hydrogel wound dressing is endowed with rapid degradation behavior in response to phenyl-2, 4, 6-trimethylbenzoylphosphinate, so that the rapid degradation of the hydrogel wound dressing in a secondary dressing change process is realized. Meanwhile, the hydrogel wound dressing can carry water-soluble drugs, bioactive factors, slow-release carriers and the like to endow the hydrogel wound dressing with the functions of antibiosis, anti-inflammation, healing promotion and the like. The hydrogel wound dressing is prepared by an ultraviolet polymerization one-step method, and has the advantages of simple process, mild reaction conditions and high preparation efficiency. The invention has good biocompatibility and great advantages in the aspect of skin injury repair.
priorityDate 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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