http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109517107-A

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filingDate 2018-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92bc3f1b0c72ef62211f52c238099a9e
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publicationDate 2019-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109517107-A
titleOfInvention A temperature-sensitive poly(propionylaminoethylacrylate-co-benzamidoethylacrylate) and its preparation method
abstract The present invention provides a temperature-sensitive poly(propionylaminoethyl acrylate-co-benzamidoethyl acrylate) and a preparation method thereof, the chemical structural formula of which is shown in formula (I), wherein, x= 0.10~0.28, y=0.72~0.90; its minimum critical solution temperature is 22.6~39.2°C; it is 2-phenyl-2-oxazoline, 2-ethyl-2-oxazoline and Acrylic acid is used as a raw material, which is prepared by ring-opening reaction first, and then free radical copolymerization. The polymer of the present invention not only has excellent temperature-sensitive properties, but also has good biocompatibility, its preparation method is simple, the conditions are mild, and the reaction is rapid, the operation is simple, and it can be used for drug controlled release, bioseparation, and immune analysis It has important research and development value in application fields that require high biocompatibility of temperature-sensitive materials.
priorityDate 2018-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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