http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109512798-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109512798-B |
| titleOfInvention | A pharmaceutical composition nanosystem for anti-tumor immunotherapy |
| abstract | The present invention designs a pharmaceutical composition nano-system for anti-tumor immunotherapy, which specifically comprises using a therapeutically effective amount of one or more perfluorocarbon compounds and one or more immune checkpoint inhibitors as an effective ingredient package contained in the albumin shell. Experiments have verified that the drug composition can open the tumor vascular barrier, increase vascular permeability, promote the infiltration of immune T cells in the tumor, and at the same time enhance the killing activity of tumor-related T cells, and increase IFN-γ, TNF-α and IL-6 The expression level of the same toxic killing factor, exerting synergistic anti-tumor immune efficacy, and providing a solution to the problem of low patient response rate during the clinical use of immune checkpoint inhibitors as a single drug. |
| priorityDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.