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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02
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filingDate 2019-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109507342-B
titleOfInvention Method for determining nitroimidazole drug residues in blood sample
abstract The invention discloses a method for determining nitroimidazole drug residues in a blood sample, which is characterized by comprising the following steps: the method comprises the following steps: (1) preparation of supramolecular solvent: stirring and centrifuging n-octanol, tetrahydrofuran and water, and taking an upper organic phase; (2) sample pretreatment: placing a blood sample in a supramolecular solvent, oscillating, extracting, centrifuging, transferring an upper-layer liquid filtering membrane, placing filtrate in a microscale sample injection bottle, adding methanol, and mixing uniformly to obtain a solution to be detected; (3) and (3) determining the nitroimidazole medicament residues in the solution to be detected by adopting ultra-performance liquid chromatography-tandem mass spectrometry. The method is simple, convenient, rapid, accurate and reliable, and can be used for analyzing and detecting the nitroimidazole medicament residues in the blood sample.
priorityDate 2019-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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