http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109503453-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4015 |
| filingDate | 2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109503453-B |
| titleOfInvention | A kind of bacterial quorum sensing inhibitor and preparation method and application thereof |
| abstract | The invention provides a bacterial quorum sensing inhibitor and a preparation method and application thereof, belonging to the technical field of medicinal chemistry. The bacterial quorum sensing inhibitor mainly includes a class of pyrrolidone derivatives with a novel structure. After research, it can significantly reduce the expression of related pathogenic factors within the scope of not inhibiting the growth of pathogenic bacteria. virulence of bacteria, and thus can be used as bacterial quorum-sensing inhibitors to control bacterial infections with quorum-sensing systems. At the same time, the compound of the present invention has a simple preparation method, mild reaction conditions, cheap and easy-to-obtain raw materials, can quickly and large-scale preparation and obtain a variety of compounds with brand-new structures, and has good economy and large-scale industrial production value. |
| priorityDate | 2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.