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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01K11-00
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filingDate 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109489854-B
titleOfInvention Nano gold cone photo-thermal reagent with temperature measurement function and preparation method thereof
abstract The invention discloses a nano gold cone photothermal reagent with a temperature measurement function and a preparation method thereof, and relates to the technical field of photothermal therapy. The nano-gold cone photo-thermal reagent comprises a nano-gold cone, a temperature-sensitive DNA stem-loop structure and a Texas red fluorescent molecule; wherein the nano gold cone and the Texas red fluorescent molecule are respectively connected to two ends of a DNA stem-loop structure; the nano-gold cone photo-thermal reagent also comprises an auxiliary chain positioned on the surface of the nano-gold cone, wherein the auxiliary chain is used for reducing the density of a DNA stem-loop structure on the surface of the nano-gold cone; the invention also discloses a preparation method of the nano gold cone photo-thermal reagent. The nano gold cone photothermal reagent has good application prospect in the field of photothermal therapy.
priorityDate 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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