http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109486897-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09a2223fab2bf82afd1b34cba8a86269 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
filingDate | 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ed5f72de278868004c5598a200e117b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28b90c65aaf2a11b8c8d84938a9d3483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12398ce9ec8b7384ff88235076e46306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_850be6b899e6a8270b2a44a218c899f9 |
publicationDate | 2019-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109486897-A |
titleOfInvention | A kind of method for stereoselective enzyme-catalyzed hydrolysis and splitting of 2-phenylpropionic acid enantiomer |
abstract | This patent discloses a method for efficiently splitting 2-phenylpropionic acid enantiomers. Using the characteristics of high activity and stereoselectivity of lipase, catalyzed hydrolysis of racemic 2-phenylpropionate in a single aqueous system to obtain (S)-2-phenylpropionic acid and (R)-2-benzene 2-phenylpropionic acid ester, which realizes the enantiomer resolution of 2-phenylpropionic acid. Both Pseudomonas cepacia lipase and Pseudomonas fluorescens lipase showed excellent stereoselectivity, and the optical purity of their products were both >99%, while Pseudomonas cepacia lipase showed higher activity and transformed rate>45%. Compared with other separation techniques, the method has the advantages of mild reaction conditions, simple operation, no solvent pollution, high product purity and low cost. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109897874-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111662898-A |
priorityDate | 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 215.