http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109486739-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-04 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-63 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-36 |
filingDate | 2018-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109486739-B |
titleOfInvention | Method for inducing vibrio parahaemolyticus to generate levofloxacin drug resistance |
abstract | The invention discloses a method for inducing vibrio parahaemolyticus to generate levofloxacin drug resistance, which comprises the following steps: sensitive strain screening, sublethal antibiotic concentration preliminary induction and continuous induction, drug-resistant strain preservation, the induced vibrio parahaemolyticus of the invention obtains levofloxacin drug resistance through verification, the MIC value of the vibrio parahaemolyticus reaches the drug-resistant standard of CLSI, namely, the MIC value of the vibrio parahaemolyticus is more than or equal to 8mg/L, and the drug resistance can be stably inherited; the induction method can quickly obtain drug-resistant strains with stable genetic characteristics, provides a reliable tool for the research of the drug-resistant mechanism of the vibrio parahaemolyticus on levofloxacin, and has good reference value and practical significance. |
priorityDate | 2018-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.