| abstract |
The present invention relates to the prediction of the development of type 2 diabetes by quantitative analysis of N-glycans attached to plasma proteins of healthy persons, which makes it possible to determine whether the person under investigation belongs to a risk group for the development of type 2 diabetes. future. The obtained quantitative percentages of all analyzed N-glycans were used as input variables for model F: F(GP1, GP2, ..., GPX; D, S) where x, d and s are the parameters of model F: X = analysis The total number of N-glycans in the ..., GPX; D, S) constants. The investigators' obtained results, F, were then compared to a threshold T, which was statistically determined and defined a threshold for an increased risk of future development of type 2 diabetes (T2D). |