| abstract |
The present invention relates to chemistry, pharmacology, in particular derivatives from phenolic or polyphenolic compounds and derivatives from phenolic or polyphenolic compounds and derivatives fused to 1,4-dihydropyridine. Preparation of a combined formulation of a tricyclic system of the diazepine type, which has effects on the central nervous system and the vascular system. These pharmaceutical compositions exhibit calcium channel modulation, and their GABAergic, antiglutamatergic, mitogenic, antioxidative, antiinflammatory and antiapoptotic effects, and can be used in the treatment of cardiovascular, cerebral, and cerebrovascular diseases. Vascular, neurodegenerative, neuropsychiatric and neurological diseases. |