http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109470691-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-76 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76 |
filingDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109470691-B |
titleOfInvention | Self-assembled aptamer/protein composite nanoprobe, preparation method, kit and application thereof |
abstract | The invention discloses a self-assembly aptamer/protein composite nano probe, a preparation method, a kit and application thereof, wherein three DNA probes are hybridized to prepare the self-assembly aptamer/protein composite nano probe, one of the three DNA probes is a DNA probe containing an aptamer sequence, and the other one is marked with horseradish peroxidase, and magnetic nanoparticles functionalized by the aptamer are used as a magnetic separation solid phase carrier for specific capture of human acute lymphoblastic leukemia T lymphocytes (CCRF-CEM) in blood and improving capture efficiency of a target object High specificity and rapid detection, and has great significance for the auxiliary diagnosis, curative effect evaluation and prognosis judgment of leukemia. |
priorityDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.