http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109467607-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4748 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109467607-B |
| titleOfInvention | Acid-sensitive fusion peptide targeting tumor and application thereof |
| abstract | The invention discloses an acid-sensitive fusion peptide targeting a tumor and application thereof, wherein the fusion peptide is formed by connecting a low-pH insertion peptide and a fourth structural domain of a tumor surface antigen Her 2. The fusion peptide can be inserted into a tumor cell membrane in an acidic environment and displays the fourth domain of Her2 on the cell surface, so that the fusion peptide is successfully recognized by a tumor medicament trastuzumab, and the fusion peptide can effectively treat tumors. The research result of the invention overcomes the defect that the existing tumor medicament can only treat one type of cancer or can only treat one type of cancer, and the trastuzumab has the treatment efficacy on all cancers by marking the surface of the tumor with the fusion peptide of the invention, which has milestone significance for clinically treating the tumor. |
| priorityDate | 2017-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 309.