http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109467596-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate | 2018-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109467596-B |
| titleOfInvention | Application of transcription factor SP1 in regulation and control of pig RTL1 gene expression |
| abstract | The invention provides application of a transcription factor SP1 in regulation and control of pig RTL1 gene expression. According to the invention, RTL1 is taken as a research object, a core promoter region of RTL1 is found by constructing a porcine RTL1 gene promoter dual-luciferase reporter gene recombinant plasmid; then verifying the interaction between the transcription factor SP1 and the core promoter region of RTL 1; then constructing an SP1 overexpression vector and synthesizing small interfering RNA, and detecting the influence of SP1 on RTL 1; a transcription factor SP1 binding site mutant type fluorescent expression vector SP1-mut is constructed to detect luciferase activity after PK15 cells and C2C12 cells are transfected. The invention firstly proves the influence of the transcription factor SP1 on the transcription regulation of the RTL1 gene, brings deeper cognition for the expression regulation of the RTL1, is applied to the improvement of the meat quality characteristics of livestock and the research of a muscle development molecule regulation mechanism, and has better application prospect. |
| priorityDate | 2018-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.