http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109456992-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-002 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 |
| filingDate | 2017-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109456992-B |
| titleOfInvention | Multifunctional gene expression platform regulated by protocatechuic acid and its application |
| abstract | The invention discloses a multifunctional gene expression platform regulated by green tea metabolite protocatechuic acid. The platform involves a switch system regulated by protocatechuic acid, that is, the on-off system of protocatechuic acid-regulated genes is precisely regulated by protocatechuic acid, and the switch system includes the "on" system regulated by protocatechuic acid and the "on" system regulated by protocatechuic acid. The "off" system. The invention also provides eukaryotic expression vectors, mammalian cell lines and microcapsules comprising the switch system. In addition, the present invention also discloses that the multifunctional platform can regulate the precise expression and release of insulin or glucagon-like peptides for diabetes treatment; the gene expression regulation platform can be used to build complex biological computers and regulate CRISPR/Cas9 or CRISPR/ dCas9 system-mediated gene editing and activation or repression of gene expression. The invention provides a powerful novel gene expression regulation tool for gene therapy and cell therapy. |
| priorityDate | 2017-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 605.