http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109439630-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2304 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-115 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0639 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 |
| filingDate | 2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109439630-B |
| titleOfInvention | Method for regulating and controlling auxiliary chaperone molecules to further regulate and control dendritic cells to be in specific functional mature state and application |
| abstract | The invention relates to a method for regulating dendritic cells to be in a specific functional mature state by regulating auxiliary chaperone molecules and application thereof. The invention proves that the auxiliary chaperone molecules HSP70L1 and DNAJC2 have a dynamic rule of specific expression in the differentiation from human monocytes to dendritic cells, and on the basis, specific time is selected to promote the expression of the molecules or inhibit the expression of the molecules, so that the differentiation and functional maturation of the human monocyte-derived dendritic cells can be respectively inhibited and promoted, and the dendritic cells can be used for further obtaining T cells with changed immune response capability. Therefore, the designed medicine can be applied to the treatment fields of autoimmune diseases, anti-tumor, anti-virus and the like, and has wide application prospect. |
| priorityDate | 2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 803.