Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57488 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate |
2018-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-109438576-B |
titleOfInvention |
Preparation and application of anti-human CD47 monoclonal antibody |
abstract |
The invention belongs to the field of antibodies, and particularly relates to a preparation method and application of an anti-human CD47 monoclonal antibody. The invention discloses a highly variable region sequence of the monoclonal antibody. The anti-human CD47 monoclonal antibody provided by the invention has good binding activity, can effectively recognize the expression of CD47 on the surface of a tumor cell, and can effectively recognize the recombinant human CD47 extracellular region protein at the protein level. Meanwhile, the epitope identification of the monoclonal antibody is clear, and the monoclonal antibody can be effectively applied to the diagnosis of CD47 target molecules and the preparation and development of anti-human CD47 monoclonal antibody medicines. |
priorityDate |
2018-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |