http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109438544-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9353da21ba23e86e687a465920a68849 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04 |
| filingDate | 2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2abf93a20b3d1f38ad2d4725934cba7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f126b8c0b6f6a8d2678b86b69eb403a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07da4eaedeffaf36ba4107021dfbf8e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdf450c704108814638bbf635e307b23 |
| publicationDate | 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109438544-A |
| titleOfInvention | Liriodendron chinensis leaf extract and its extraction method and its application in the preparation of procoagulant and hemostatic drugs |
| abstract | The present invention discloses a method for extracting Liriodendron sinensis leaf extract, which specifically includes: 1) leaching the leaves of Euphorbia sinensis with ethanol, and concentrating under reduced pressure to obtain a total extract; 2) using petroleum ether and ethyl acetate respectively. The total extract was extracted, and the ethyl acetate fraction was subjected to silica gel column chromatography, followed by gradient elution with dichloromethane-methanol to obtain six components, which were labeled as F1 to F6 according to the polarity of the obtained components from small to large; 3 ) Pass component F5 through an ODS open column, and use methanol-water gradient elution to obtain ten components, which are labeled as components 1 to 10 in order of polarity from small to large, and component 4 is the goose Palm Chai Leaf Extract. According to the identification, the present invention finds that the active ingredient of the leaf extract is 3-oxo-sulfonic acid betulinic acid, and the biochemical indexes of the leaf extract on heparin sodium in rats are measured by rats, and its promoting effect is investigated. The effect of coagulation and hemostasis. The results show that the effect of promoting blood coagulation and hemostasis in rats is remarkable. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111072748-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111072748-B |
| priorityDate | 2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.