http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109438332-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ecda51df432101d6989a3c81fa399da0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-55 |
| filingDate | 2018-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50260d151c8945cc8d0404c2024361bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_525d5e5c24ef19ae82903a3364fe3338 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f74d555543c9a032f38454b3471fc00 |
| publicationDate | 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109438332-A |
| titleOfInvention | A new crystal form A of atorvastatin and its preparation method and application |
| abstract | The invention discloses a new crystal form A of atorvastatin and a preparation method and application thereof. The crystal of the new crystal form A is subjected to X-ray powder diffraction, and the diffraction peak position 2θ (±0.20°) is used as the characteristic parameter of the spectrogram , the diffraction peak positions 2θ are in sequence: 8.49°, 9.21°, 10.04°, 12.52°, 16.99°, 17.55°, 18.41°, 19.33°, 19.96°, 21.34°, 23.30°. The preparation method is as follows: adding atorvastin to a solvent, heating up and dissolving to obtain atorvastatin solution, crystallizing by using a temperature difference method, separating solid-liquid and drying the solid to obtain a new crystal form A of atorvastatin . The new crystal form A of atorvastin provided by the present invention not only fills the gap in this research field, but also has the characteristics of high chemical stability, high bioavailability and comparable to the atorvastatin raw materials of Xinminle, which is very popular in domestic Further development of its dosage form or industrial production is of great significance. |
| priorityDate | 2018-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.