| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5fdd9da231b319cb1307a50593392b9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2523-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-4283 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J35-026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J37-086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-182
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-28 |
| filingDate |
2018-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37fcb928a3d408b49685211c535ad123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a65385c8f0fd76c74a8537332739151
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d073b4216923175433a1c42d9921063e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c2ff98aedb32433566d8f2cb6386af8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6b9119672283cb8c409b1ce636cd9a6 |
| publicationDate |
2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109433267-A |
| titleOfInvention |
Preparation method of drug sputum intermediate for anti-delay hair movement disorder |
| abstract |
The invention belongs to the technical field of pharmacy, and in particular relates to a preparation method of a drug sputum intermediate for anti-delay dyskinesia. The invention adopts 2-methylimidazole and copper salt as raw materials to react in methanol, and then calcinifies to prepare a carbonized imidazole skeleton copper material, and then forms polyethylene with polyvinylpyrrolidone and surfactant cetyltrimethylammonium bromide. Pyrrolidone-coated carbonized imidazole skeleton copper porous crystal material; then polyvinylpyrrolidone coated carbonized imidazole skeleton copper porous crystal material is used as a catalyst for catalyzing the condensation of 5-chloropurine with p-bromofluorobenzene to prepare 5-chloro-1‐ (4-fluorophenyl)-1H-indole; the catalyst prepared by the invention has high catalytic efficiency, and the reaction can be balanced at 4-6 hours by using about 50 parts per thousand of the weight of 5-chloropurine, and the catalyst Can be recycled. |
| priorityDate |
2018-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |