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filingDate 2018-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bae7e13708c0e664db1d4d42da74365
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publicationDate 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109432514-A
titleOfInvention Degradable magnesium alloy bone nail with scaly bone-like nanostructure coating and preparation method thereof
abstract The invention relates to a degradable magnesium alloy bone nail with a scaly bone-like nanostructure coating on the surface and a preparation method thereof. The degradable bone nail is composed of an AZ31B magnesium alloy bone nail matrix and a PLGA-bone morphogenetic protein BMP. The scaly bone-like nanostructured magnesium oxide bioceramic coating composition. The magnesium oxide bioceramic coating having the scaly bone-like nanostructure is combined with the surface of the metal substrate, and a nano-sized scaly nanostructure is constructed on the surface of the substrate by micro-arc oxidation technology. BMP is filled and loaded between the magnesium oxide scaled bone-like nanostructure layer by centrifugal force and capillary action. The preparation method comprises the following steps: firstly, the AZ31B magnesium alloy is used to process the bone nail; then the micro-arc oxidation technique is used to obtain the magnesium oxide ceramic coating with the scaly bone-like nanostructure characteristics on the surface of the substrate; finally, the centrifugal load technique is used in the magnesium oxide scale-like imitation. The PLGA-bone morphogenetic protein is loaded between the bone nanostructure layers.
priorityDate 2018-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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