Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ce61bf06f294f2f466c067ed41cc8ce |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C25D11-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C25D11-026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-022 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C25D11-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-02 |
filingDate |
2018-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bae7e13708c0e664db1d4d42da74365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1602515be069061aa10a416c0f7121dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9fc2b069cdd43196e033316020049e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30e33b3b88eb20666c2d9ac6a9d0e2e5 |
publicationDate |
2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-109432514-A |
titleOfInvention |
Degradable magnesium alloy bone nail with scaly bone-like nanostructure coating and preparation method thereof |
abstract |
The invention relates to a degradable magnesium alloy bone nail with a scaly bone-like nanostructure coating on the surface and a preparation method thereof. The degradable bone nail is composed of an AZ31B magnesium alloy bone nail matrix and a PLGA-bone morphogenetic protein BMP. The scaly bone-like nanostructured magnesium oxide bioceramic coating composition. The magnesium oxide bioceramic coating having the scaly bone-like nanostructure is combined with the surface of the metal substrate, and a nano-sized scaly nanostructure is constructed on the surface of the substrate by micro-arc oxidation technology. BMP is filled and loaded between the magnesium oxide scaled bone-like nanostructure layer by centrifugal force and capillary action. The preparation method comprises the following steps: firstly, the AZ31B magnesium alloy is used to process the bone nail; then the micro-arc oxidation technique is used to obtain the magnesium oxide ceramic coating with the scaly bone-like nanostructure characteristics on the surface of the substrate; finally, the centrifugal load technique is used in the magnesium oxide scale-like imitation. The PLGA-bone morphogenetic protein is loaded between the bone nanostructure layers. |
priorityDate |
2018-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |