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filingDate 2018-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109432508-B
titleOfInvention Decalcified bone matrix material with bone growth promoting and antibacterial functions as well as preparation method and application thereof
abstract The embodiment of the invention discloses a decalcified bone matrix material with double functions of promoting bone growth and resisting bacteria. The invention firstly obtains the polymer through atom transfer free radical reaction, and then introduces the bone growth promoting signal molecule and quaternary ammonium salt on the side chain of the polymer, the invention has the characteristics of large attachment amount and high attachment rate, the obtained polymer is further compounded with the decalcified bone matrix in a covalent bond mode, and the bone growth promoting signal molecule with the bone growth promoting function and the quaternary ammonium salt with the antibacterial function can be effectively and firmly loaded on the decalcified bone matrix, thereby obviously improving the bone growth promoting activity of the decalcified bone matrix, simultaneously having the antibacterial function, and the material can be applied to the repair and reconstruction of bone defect and has wide application prospect.
priorityDate 2018-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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