http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109432054-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2018-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109432054-B |
| titleOfInvention | Method for preparing risperidone-containing sustained-release microspheres |
| abstract | The invention provides a method for preparing risperidone sustained-release microspheres, which comprises the following steps: (1) weighing a certain amount of PLA, controlling the melting temperature A, and heating to obtain the PLA in a molten state; (2) weighing a certain amount of risperidone powder, and mixing the risperidone powder with PLA in a molten state to obtain a risperidone PLA mixture; (3) controlling the melt extrusion temperature B, and melt extruding the risperidone PLA mixture to obtain a hot melt extrusion material; (4) controlling the crushing temperature C, cooling and crushing the hot-melt extrudate, and sieving to obtain the sustained-release microspheres containing risperidone; washing, centrifuging and freeze-drying to obtain the finished microsphere product. |
| priorityDate | 2018-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.