| abstract |
The invention discloses a local injection preparation of rapamycin and a preparation method thereof, which are used for treating vascular malformation with severe lesions and deep under the skin, and have the effects of long-term sustained release, and have good compatibility and metabolism in the body. The rapamycin local injection preparation comprises 0.02-0.05 g of rapamycin, 1-3 g of an organic solvent, 6-10 g of phospholipid, 8-12 g of glyceride and 0.6-1.2 g of a stabilizer; The mycin is dissolved in an organic solvent, and then a phospholipid, a glyceride, and a stabilizer are added, and the mixture is uniformly mixed to obtain a local injection preparation of rapamycin. |