http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109419771-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 |
filingDate | 2017-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109419771-B |
titleOfInvention | Testosterone undecanoate sustained-release pharmaceutical composition, and preparation method and application thereof |
abstract | The invention belongs to the technical field of medicines, and relates to testosterone undecanoate suspension, and a preparation method and application thereof. Specifically, the invention relates to a testosterone undecanoate suspension comprising testosterone undecanoate, a stabilizer and water, wherein: the content of testosterone undecanoate is 10% -50%; the particle size of the testosterone undecanoate meets the following requirements: d10 is 0.2-0.5 μm, D50 is 0.5-1.5 μm, and D90 is 2.2-6.0 μm; the stabilizer comprises a first stabilizer and a second stabilizer, and the weight ratio of the first stabilizer to the second stabilizer is (1-10): (1-20), and the weight ratio of the testosterone undecanoate to the stabilizer is (1-20): (1-20). The testosterone undecanoate suspension has good stability, good redissolution condition after sedimentation, high bioavailability and small irritation, and can stably maintain the hormone level in the body for a long time. |
priorityDate | 2017-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.