| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b76c30c1bbba1b914128ccb35683e0b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H05K999-99 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2017-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57b632ef8686576261ee42a4489bff83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d30ff663c9aa376138eb5f97256f7919
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e674786b089a6806e0d4bdf8704e4ea |
| publicationDate |
2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109414495-A |
| titleOfInvention |
Therapeutic inhibitors of EBV-related tumors with tailored responsive optical imaging |
| abstract |
A nuclear permeability small molecule inhibitor L 2 P 4 is provided (wherein L 2 is 4-(4-(diethylamino)styryl)-N-carboxymethylpyridinium chloride and P 4 is a CAhxYFMVFGGRrRK-containing amino acid sequences, and they are coupled by amide bonds) and methods for their synthesis, the nuclear-permeable small molecule inhibitors efficiently target the dimerization interface of EBNA1, a process critical for the growth of EBV and related tumors . Also provided are methods of treating and imaging EBV-related cancers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022258017-A1 |
| priorityDate |
2016-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |