http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109400868-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-2609 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-28 |
| filingDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109400868-B |
| titleOfInvention | Synthesis method of polyethylene glycol mono-anisole compound |
| abstract | The invention relates to a synthesis method of a polyethylene glycol mono-anisole compound, which comprises the following steps: step S1, adding an organic solvent into the reactor, adding a mixed alkali formed by fixed matching and mixing, closing the reactor, and treating the reactor to enable the reactor to be in an anhydrous and oxygen-free environment; step S2, opening a feed valve, adding 2-benzyloxy ethanol, stirring, setting the temperature to be 20-70 ℃, and reacting for 1-12 hours; step S3, turning off stirring and heating, cooling the reactor to below-15 ℃ by using liquid nitrogen, and continuously treating the reactor to ensure anhydrous and anaerobic operation; step S4, opening a feed valve, adding ethylene oxide, setting the temperature to be 30-70 ℃, and reacting for 36-72 h; and step S5, after the reaction time is up, carrying out post-treatment on the product obtained in the step S4 to obtain a pure polyethylene glycol mono-anisole compound. The method not only can make the reaction mild, reduce the operation risk, realize the industrial production, but also can improve the product yield. |
| priorityDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.