http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109400629-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-10 |
| filingDate | 2018-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109400629-B |
| titleOfInvention | Indole spirooxazine heterocyclic compound and preparation method thereof |
| abstract | The invention provides a novel indole spirooxazine heterocyclic compound and a preparation method thereof. In the method, indole diazo compound and benzisoxazole are used as reaction substrates to react under the catalysis of transition metal, and indole spiro oxazine heterocyclic compounds are prepared with high efficiency through one-step reaction. The indole spiroheterocyclic compounds obtained by this method have potential medicinal activities, and the product molecules contain halogens, carbonimide double bonds and sulfonyl groups, which are prone to various additional transformations, thereby preparing compounds containing more complex structures. Organic compounds of the indole ring system. The method has the advantages of easily available raw materials, simple reaction system, good chemical selectivity, no need for strict anhydrous and anoxic conditions, strong operability, and the easily enlarged ten-gram scale does not obviously affect the yield of the reaction. The functional group of the reaction has good compatibility, wide substrate applicability, stable product, easy separation and purification, suitable for industrial scale-up preparation, and has good application potential. |
| priorityDate | 2018-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.