http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109395162-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 |
| filingDate | 2018-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109395162-B |
| titleOfInvention | Preparation method of natural protein-based bionic structure bone scaffold |
| abstract | The invention discloses a preparation method of a natural protein-based bionic structure bone scaffold, which comprises the steps of taking silk fibroin and wool protein as main raw materials, uniformly mixing a silk fibroin solution and glycerol according to a mass ratio of 60-120: 20-60, injecting the mixture into a bone scaffold mold, slowly injecting a wool keratin solution into the mixed solution, freezing and storing the mixed solution at 40 ℃ below zero to 20 ℃ below zero and at 1.0 multiplied by 10 5 And (3) carrying out vacuum freeze drying at-1.0 Pa and-72-5 ℃ to obtain the silk fibroin/wool keratin bionic bone scaffold material. The prepared scaffold material is similar to an autologous bone structure, the porosity reaches 70-95%, the pore size distribution is uniform, the outer layer is compact, the pore size is small, the diameter range is 30-150 mu m, certain mechanical support performance can be provided for the scaffold material, the inner pore size is large, the diameter range is 150-600 mu m, and the scaffold material is suitable for migration, attachment and proliferation of cells. |
| priorityDate | 2018-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.