http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109394782-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-55 |
| filingDate | 2018-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109394782-B |
| titleOfInvention | Cholesterol derivative modified poly-molybdenum oxide cluster hybrid and preparation and application thereof |
| abstract | The invention discloses a cholesterol derivative modified poly-molybdenum oxide cluster hybrid with a chemical formula of [ (C) 4 H 9 ) 4 N] 3 {(MnMo 6 O 18 )[CNH(CH 2 O) 3 C 72 H 116 N 3 O 8 ] 2 (ii) having a structural formula represented by the following formula (i): wherein: POM = MnMo 6 O 18 ，TBA=[(C 4 H 9 ) 4 N] + . The hybrid is represented by the chemical formula [ (C) 4 H 9 ) 4 N] 3 (MnMo 6 O 18 )[(OCH 2 ) 3 CNH 2 ] 2 Poly-molybdenum oxide cluster, 3' -bicholesterol succinimidyl monoester dipropylamino succinic acid monoamide, 1-ethyl- (3-dimethylaminopropyl) carbodiimide hydrochloride, N -hydroxysuccinimide and triethylamine as raw materials, and reacting in a mixed solvent system of chloroform and acetonitrile to obtain the compound. The cholesterol derivative modified poly-molybdenum oxide cluster hybrid can be applied to preparation of anti-breast cancer drugs and has strong poisoning effect on human breast cancer cell lines (MCF-7). |
| priorityDate | 2018-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.