http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109394726-B

Outgoing Links

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filingDate 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109394726-B
titleOfInvention A kind of omeprazole sodium bicarbonate capsule and preparation method thereof
abstract The invention discloses a kind of omeprazole sodium bicarbonate capsules, raw material including following mass parts: Omeprazole 20 or 40 parts, 400-500 parts of sodium bicarbonate, 600-700 parts of magnesium hydroxide, 20~30 parts of croscarmellose sodium, 0.3~0.6 part of sodium stearyl fumarate;Wherein, Omeprazole uses three kinds of partial sizes;Sodium bicarbonate uses two kinds of partial sizes;The partial size of the magnesium hydroxide is 150~180 μm.It is 1~10 μm that preparation method, which includes the following: 1) by particle diameter distribution, the croscarmellose sodium of 10~80 μm of Omeprazole, the sodium bicarbonate that particle diameter distribution is 10~20 μm, 1/2-2/3 mass carries out dry granulation after mixing;2) Omeprazole, the sodium bicarbonate that partial size is 150~180 μm, magnesium hydroxide, the croscarmellose sodium of surplus and sodium stearyl fumarate that particulate matter, particle diameter distribution are 80~100 μm are uniformly mixed, are packed into capsule to obtain the final product.
priorityDate 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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