http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109394726-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
filingDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109394726-B |
titleOfInvention | A kind of omeprazole sodium bicarbonate capsule and preparation method thereof |
abstract | The invention discloses a kind of omeprazole sodium bicarbonate capsules, raw material including following mass parts: Omeprazole 20 or 40 parts, 400-500 parts of sodium bicarbonate, 600-700 parts of magnesium hydroxide, 20~30 parts of croscarmellose sodium, 0.3~0.6 part of sodium stearyl fumarate;Wherein, Omeprazole uses three kinds of partial sizes;Sodium bicarbonate uses two kinds of partial sizes;The partial size of the magnesium hydroxide is 150~180 μm.It is 1~10 μm that preparation method, which includes the following: 1) by particle diameter distribution, the croscarmellose sodium of 10~80 μm of Omeprazole, the sodium bicarbonate that particle diameter distribution is 10~20 μm, 1/2-2/3 mass carries out dry granulation after mixing;2) Omeprazole, the sodium bicarbonate that partial size is 150~180 μm, magnesium hydroxide, the croscarmellose sodium of surplus and sodium stearyl fumarate that particulate matter, particle diameter distribution are 80~100 μm are uniformly mixed, are packed into capsule to obtain the final product. |
priorityDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.