http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109394723-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4858 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 |
filingDate | 2017-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109394723-B |
titleOfInvention | Dutasteride soft capsule and preparation method thereof |
abstract | The invention discloses a dutasteride soft capsule with good dissolution, stable quality and good safety, wherein the content components of the dutasteride soft capsule comprise, by weight, 0.076-0.230% of dutasteride, 74.49-91.52% of caprylic triglyceride, 7.31-21.93% of surfactant, 1.08-3.32% of suspending agent and 0.01-0.032% of antioxidant dibutyl hydroxytoluene, and the capsule shell components of the soft capsule comprise 31.86-53.10% of gelatin, 9.56-15.93% of plasticizer glycerol, 1.60-5.31% of disintegrating agent, 0.13-0.22% of opacifier and water. The invention also discloses a preparation process of the dutasteride soft capsule, which effectively improves the dissolution condition and the quality stability of the dutasteride soft capsule by controlling the heating temperature of contents and controlling the drying condition of the soft capsule. |
priorityDate | 2017-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.