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filingDate 2017-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109394723-B
titleOfInvention Dutasteride soft capsule and preparation method thereof
abstract The invention discloses a dutasteride soft capsule with good dissolution, stable quality and good safety, wherein the content components of the dutasteride soft capsule comprise, by weight, 0.076-0.230% of dutasteride, 74.49-91.52% of caprylic triglyceride, 7.31-21.93% of surfactant, 1.08-3.32% of suspending agent and 0.01-0.032% of antioxidant dibutyl hydroxytoluene, and the capsule shell components of the soft capsule comprise 31.86-53.10% of gelatin, 9.56-15.93% of plasticizer glycerol, 1.60-5.31% of disintegrating agent, 0.13-0.22% of opacifier and water. The invention also discloses a preparation process of the dutasteride soft capsule, which effectively improves the dissolution condition and the quality stability of the dutasteride soft capsule by controlling the heating temperature of contents and controlling the drying condition of the soft capsule.
priorityDate 2017-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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