http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109384787-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 |
| filingDate | 2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109384787-B |
| titleOfInvention | Method for synthesizing hydrogenated pyridine spiro indoline ring under catalysis of monovalent silver |
| abstract | The invention provides a synthesis method for generating a hydrogenated pyridine spiro indoline ring by using an indole-containing tryptamine alkyne amide substrate under the room temperature condition under the action of monovalent silver and a reducing agent, wherein the reaction general formula is as follows, and R in the formula 1 ，R 2 ，R 3 ，R 4 As described in the claims and specification. The silver catalyst required by the reaction is one of silver trifluoromethanesulfonate, silver hexafluoroantimonate, silver tetrafluoroborate and silver bis (trifluoromethanesulfonyl) imide. The reducing agent required for the reaction is hans ester. The media required for the reaction are: toluene. The reaction is carried out by stirring at room temperature, and the method has the advantages of easily available raw materials, simple operation, wide application range, good atom economy, green reaction and low cost. |
| priorityDate | 2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.