http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109371043-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56905 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-02 |
filingDate | 2018-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109371043-B |
titleOfInvention | Babesia voles 2D33 and 2D36 antigenic proteins and their applications |
abstract | The present invention discloses Babesia voles 2D33 and 2D36 antigen proteins and applications thereof. The amino acid sequences thereof are respectively shown in SEQ ID NO: 4 or SEQ ID NO: 6, and the coding gene sequences thereof are shown in SEQ ID NO: 3 or SEQ ID NO: 5 shown. The invention obtains the immune response spectrum of Babesia voles. In the protein chip analysis of specific IgG antibodies, the recombinant proteins Bm2D33 and Bm2D36 both show the effect of significantly decreasing the immune response with mouse serum after acute stage, and can be used for detection Or diagnose the disease transition process of babesiosis from acute phase to chronic phase. Moreover, the recombinant proteins Bm2D33 and Bm2D36 showed high specificity in the cross-reaction test with human serum of falciparum malaria, and the specificity was 100%. |
priorityDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 482.