http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109369738-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
filingDate | 2018-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109369738-B |
titleOfInvention | Preparation method of fondaparinux sodium monosaccharide intermediate |
abstract | The invention discloses a preparation method of fondaparinux sodium monosaccharide intermediate, which comprises the steps of taking glucosamine protected at C4 and C6 as a raw material, carrying out methylation, amidation and benzylation to obtain methyl 3-O-benzyl-4, 6-O-benzylidene-2- (benzyloxycarbonyl) amino-2-deoxy-alpha-D-glucopyranoside, and carrying out dehydroxylation protecting group protection reaction to obtain fondaparinux sodium monosaccharide fragment intermediate methyl3-O-benzyl-2- (benzyloxycarbonyl) amino-2-deoxy-alpha-D-glucopyranoside. The preparation method has the advantages of simple process, less side reaction impurities and high yield, and is suitable for large-scale preparation of fondaparinux sodium in order to meet the requirement of industrial production of fondaparinux sodium. |
priorityDate | 2018-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.