http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109369664-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2018-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109369664-B |
| titleOfInvention | Rhodamine acylhydrazone derivative, preparation method and application thereof, and fluorescent probe |
| abstract | The invention provides a rhodamine acylhydrazone derivative, a preparation method and application thereof, and a fluorescent probe, and belongs to the field of organic synthesis. The invention takes 4-morpholine benzaldehyde and rhodamine 6G hydrazide as reactants, and the rhodamine acylhydrazone derivative can be obtained through condensation reaction; the rhodamine acylhydrazone derivative has a structure shown in a formula I, is very sensitive to pH, does not emit obvious fluorescence when the pH is greater than 4.0, emits obvious green fluorescence when the pH is less than 4.0, and generates a jump in the range of pH 3.0-4.0; the rhodamine acylhydrazone derivative provided by the invention can target lysosomes of cells and can be used for distinguishing normal cells and tumor cells by fluorescence. |
| priorityDate | 2018-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.