http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109369514-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C41-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-127 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-30 |
filingDate | 2018-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109369514-B |
titleOfInvention | Synthetic method of six-membered carbocyclic ring derivative |
abstract | The invention provides a synthesis method of a six-membered carbocyclic ring derivative, belonging to the technical field of organic synthesis. The synthesis method comprises the following steps: under the protection of inert gas, reacting a compound of a formula (I-1), a compound of a formula (II) and a compound of a formula (III) in an organic solvent under the action of a catalyst and a cocatalyst to obtain a six-membered carbocyclic ring derivative with a compound structure of the formula (IV-1); x is C or N; when X is N, R 1 、R 2 Each independently selected from a hydrogen atom, substituted or unsubstituted C 1 ‑C 10 An alkyl group; when X is C, R 1 Independently selected from substituted or unsubstituted C 1 ‑C 6 An alkoxy group; r 2 Independently selected from substituted or unsubstituted C 1 ‑C 10 An alkyl group; r 3 And R 4 Each independently selected from substituted or unsubstituted alkyl groups. The method has the advantages of wide raw material application range, mild reaction conditions and good atom economy, and is widely applied to the field of chemical and pharmaceutical industry. |
priorityDate | 2018-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.