http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109364304-B

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filingDate 2018-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109364304-B
titleOfInvention Method for preparing degradable uniform multifunctional biological bionic scaffold through 3D printing
abstract The invention provides a method for preparing an inorganic doped material for bone repair, which comprises the following steps: uniformly mixing polyester and a polycarboxyl compound in a solid phase manner, and adding the mixture into a double-screw extruder for mixing materials in a circulating manner, wherein the molar ratio of the polycarboxyl compound to the polyester is 0.1-20, the temperature of the materials is controlled to be 50-150 ℃, and the materials are continuously extruded for 5-200 min under the vacuum condition of 1-100 KPa, so that the polyester with the end modified by carboxylation is obtained; and adding inorganic bone inducing material particles into the double-screw extruder, wherein the addition amount of the inorganic bone inducing material is 1-30% of the weight of the polyester, controlling the temperature of the material at 50-150 ℃, and continuously extruding the material for 5-200 min under a vacuum condition to finally obtain the inorganic doped material for bone repair. The invention also provides a method for preparing the bone repair bionic scaffold by using the inorganic doped material through 3D printing. The method provided by the invention realizes uniform dispersion of inorganic materials in nanoscale under the solvent-free condition, has the advantages of simple process, low production cost, no generation of three wastes, environmental friendliness and suitability for industrial and continuous production.
priorityDate 2018-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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