http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109364081-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2018-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109364081-B |
| titleOfInvention | Application of pyrimidine derivative in preparation of medicine for treating thyroid cancer |
| abstract | The invention discloses an application of a pyrimidine derivative in treating thyroid cancer. Thyroid cancer is a high-incidence endocrine malignant tumor, and the incidence rate and mortality data of cancer issued by the cancer prevention and control center of China in 2018 show that about 17 ten thousand cases of thyroid cancer are newly issued in China in 2014, and about 0.8 ten thousand cases of thyroid cancer death are discovered. At present, fewer drugs for effectively treating thyroid cancer are available, and the clinical requirements cannot be met. The invention discovers that the partial pyrimidine derivatives have obvious inhibition effect on human thyroid cancer B-CPAP cells, and can be used for preparing the medicine for treating thyroid cancer; the mother nucleus and the substituent of the pyrimidine derivative both significantly influence the drug effect on thyroid cancer. |
| priorityDate | 2018-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.